Thanks for that comment, Guy. I have asked the Royal Children's Hospital medicine whether or not there was ethics clearance before these hormonal interventions were introduced as routine, but they didn't answer.
Because these are usually one off applications, some evidence of activity and safety but not necessarily to the TGA/PBS standard but for this carte blanche indefinite approval that they appear to have received for gender drugs I would have thought they should demand rock solid evidence which they obviously have not received because there is none.
Thanks for that comment, Guy. I have asked the Royal Children's Hospital medicine whether or not there was ethics clearance before these hormonal interventions were introduced as routine, but they didn't answer.
I don’t believe they would go to an ethics committee. In my Hospital you would need to apply to the Hospital Medicines Formulary committee.
It would be good to ask them how they justify using drugs only approved for Breast Cancer and Prostate cancer, in children.
What kind or quality of evidence would a medicines formulary committee require?
Because these are usually one off applications, some evidence of activity and safety but not necessarily to the TGA/PBS standard but for this carte blanche indefinite approval that they appear to have received for gender drugs I would have thought they should demand rock solid evidence which they obviously have not received because there is none.